Wiley KnowItAll Mass Spec Training

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There were significant improvements in the Wiley KnowItAll software for GCMS identificaitions in the 2025 Revision.  The following bried video demonstates the main improvements.

Brief Video of 2025 Updates (2 min)

My training videos and associated handouts covering basic and advanced EI GCMS topics in MS Expert and associated programs should be very helpful to both new and current users.  Updated videos are shown for Pt. 1-3, but the other older videos created for the 2023 version are still relevant.  The Wiley Registry is also supplied in NIST format and can be utilized with the NIST26 software and NIST libraries (see link).

Knowitall is a vendor neutral data processing solution for spectral analyses which is very valuable in unknown identifications.  It processes IR, Raman, MS, NMR, and UV data employing a large number of file formats (>170) and a total of 2.5 million reference spectra.

~264K IR, 25K Raman, ~1.25M EI mass spec, 894K NMR, and 30K UV

Highlights:

-Deconvolution/very fast library searching of accurate/nominal mass GC-MS data
-Easy manual processing of nominal and accurate mass GC-MS data
-Fast EI searches of >1.2 million spectra in <0.5 seconds
-Amazing adaptive search for unknown ID by extending usefulness of all libraries
-Transfer structures and spectra between NIST search and KnowItAll
-Easy structure drawing and structure searches
-Conversion of NIST user libraries to Wiley format

-Easy creation of libraries using links to MS interpreter and PubChem
-Quantitative EI GC-MS

YouTube MS Training Videos:
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MS Training Video Handouts:
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Other Resources:
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