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Automated non-targeted LC-MS/MS analysis capabilities were added to Wiley KnowItAll 2025.  The software contains tools to identify, analyze, and manage LC-MS/MS (tandem) data.  It supports a variety of vendor data file formats.

In addition, Wiley KnowItAll Software supports GC-MS, NMR, IR, Raman, and UV-Vis data processing and spectral analyzes.  Thus, it is a vendor neutral solution with a common interface.

Below is a very short video demonstrating the software and a more detailed Wiley webinar.

Short Demo (~1.5 min)
YouTube Detailed Webinar (~30 minutes)

Additonal Resources:

Wiley KnowItAll Software Training Course All Topics
LC Expert Training Only (PDF File)
Additional LC-MS/MS Demonstration Files in Agilent and Thermo Format
Wiley KnowItAll GC-MS Software, Drawing, Library Creation, etc.